Lena Friberg

Professor at Department of Pharmaceutical Biosciences, Research; Pharmacometrics

Email:
lena.friberg[AT-sign]farmbio.uu.se
Telephone:
+4618-471 4685
Mobile phone:
+46 70 4250203
Visiting address:
Room BMC B3:4 Biomedicinskt centrum BMC, Husargatan 3
Postal address:
Box 591
751 24 UPPSALA

Short presentation

Lena Friberg is since 2014 a Professor in Pharmacometrics. Her research is on developing pharmacokinetic and pharmacodynamic models and concepts, with a primary focus on anticancer drugs and antibiotics. The models are considering both desired effects and adverse events and aim to have value for both drug development and drug usage.

Keywords: cancer antibiotics antibiotic resistance non-linear mixed effects modelling pharmacokinetics pharmacometrics pharmacodynamics anticancer therapy bacterial infections drug development drug usage

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My courses

Biography

Dr. Friberg is since 2014 a Professor in Pharmacometrics. She holds a Master degree in Pharmaceutical Sciences and obtained a PhD in Pharmacokinetics and Drug Therapy from Uppsala University in 2003. During 2003-2008 she was supported by a grant from Knut & Alice Wallenberg foundation as a postdoc research fellow at the University of Queensland, Australia, and as a researcher at Uppsala University. In 2007 she became Docent (Associate professor) in Pharmacometrics. During 2008-2011 she was a Senior lecturer in Pharmacokinetics and thereafter a Senior lecturer in Pharmacometrics.

Lena has developed population pharmacokinetic (PK) and pharmacodynamic (PD) models of desired effects and adverse events in a range of therapeutic areas, primarily for oncology and bacterial infections, but also for CNS diseases, degenerative diseases, QT-prolongation, etc. Her research is focused on PK and PKPD‐models as well as pharmacometric concepts of value for translation of drug effects from preclinical (in vitro and in vivo) to patients and from early to late clinical development, and for optimizing clinical usage of drugs.

Dr Friberg has published >130 peer-reviewed research articles and has an h-index >40. She is currently the main supervisor of six PhD students and is mentoring two postdocs. She holds competitive grants from Swedish Research Council, Swedish Cancer Society, Uppsala Antibiotic Center, Innovative Medicines Initiative (IMI), IMI 2 Join Undertaking and Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN). In 2008 she received the Segré Prize from EUFEPS for “distinct research in the Pharmacokinetic-Pharmacodynamic area” and was appointed "Key Scientist" by Vinnova/BioSweden. In 2016 she received the Innovation award in Pharmacometrics from ISoP. Since 2012 she is deputy editor-in-chief of the journal CPT: Pharmacometrics & Systems Pharmacology.

Dr Friberg is teaching undergraduate and master students in Pharmacokinetics, Pharmacodynamics and Pharmacometrics. She also gives courses to professionals on PKPD-modeling.

Publications

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