Jonathan Cedernaes
Researcher at Institutionen för medicinska vetenskaper; Transplantation och regenerativ medicin
- E-mail:
- jonathan.cedernaes@medsci.uu.se
- Visiting address:
- Akademiska sjukhuset, ingång 40, 5 tr
751 85 Uppsala - Postal address:
- Akademiska sjukhuset, Ingång 40, 5 tr
751 85 UPPSALA
Associate professor at Institutionen för medicinsk cellbiologi; Forskargrupp Per-Ola Carlsson
- E-mail:
- jonathan.cedernaes@mcb.uu.se
- Visiting address:
- BMC
Husargatan 3
751 23 Uppsala - Postal address:
- Box 571
751 23 UPPSALA
- Academic merits:
- PhD
- ORCID:
- 0000-0002-9052-8372
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Short presentation
The main focus of our research group at the Department of Medical Sciences and Medical Cell Biology at Uppsala University is to determine the underlying mechanisms and adverse metabolic and neurocognitive effects of disrupted sleep and circadian rhythms in humans.
Keywords
- adipose tissue
- appetite regulation
- circadian disruption
- core clock genes
- exercise
- obesity
- peripheral metabolism
- skeletal muscle
- sleep deprivation
- type 2 diabetes
Publications
Selection of publications
- Acute sleep loss alters circulating fibroblast growth factor 21 levels in humans (2022)
- Meal and Sleep Timing before and during the COVID-19 Pandemic (2021)
- Social Jetlag Changes During the COVID-19 Pandemic as a Predictor of Insomnia - A Multi-National Survey Study (2021)
- Effects of acute sleep loss on diurnal plasma dynamics of CNS health biomarkers in young men (2020)
- NAD+ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging (2020)
- The role of exercise-induced peripheral factors in sleep regulation (2020)
- Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron (2019)
- Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans (2018)
- Aiding sleep in type 2 diabetes (2018)
- Candidate mechanisms underlying the association between sleep-wake disruptions and Alzheimer's disease (2017)
- Gut microbiota and glucometabolic alterations in response to recurrent partial sleep deprivation in normal-weight young individuals (2016)
- Sleep restriction alters plasma endocannabinoids concentrations before but not after exercise in humans (2016)
- A single night of partial sleep loss impairs fasting insulin sensitivity but does not affect cephalic phase insulin release in young men (2016)
- Self-reported sleep disturbance is associated with Alzheimer's disease risk in men (2015)
- Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men (2015)
- Short Sleep Makes Declarative Memories Vulnerable to Stress in Humans (2015)
- Determinants of Shortened, Disrupted, and Mistimed Sleep and Associated Metabolic Health Consequences in Healthy Humans (2015)
- Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men (2014)
- Increased Impulsivity in Response to Food Cues after Sleep Loss in Healthy Young Men (2014)
Recent publications
- Habitual Short Sleep Duration, Diet, and Development of Type 2 Diabetes in Adults (2024)
- OSA Is Associated With the Human Gut Microbiota Composition and Functional Potential in the Population-Based Swedish CardioPulmonary bioImage Study (2023)
- Exposure to a more unhealthy diet impacts sleep microstructure during normal sleep and recovery sleep (2023)
- A weighted blanket increases pre-sleep salivary concentrations of melatonin in young, healthy adults (2023)
- Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals. (2023)
All publications
Articles
- Habitual Short Sleep Duration, Diet, and Development of Type 2 Diabetes in Adults (2024)
- OSA Is Associated With the Human Gut Microbiota Composition and Functional Potential in the Population-Based Swedish CardioPulmonary bioImage Study (2023)
- Exposure to a more unhealthy diet impacts sleep microstructure during normal sleep and recovery sleep (2023)
- A weighted blanket increases pre-sleep salivary concentrations of melatonin in young, healthy adults (2023)
- Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals. (2023)
- Acute sleep loss alters circulating fibroblast growth factor 21 levels in humans (2022)
- Effects of curtailed sleep on cardiac stress biomarkers following high-intensity exercise. (2022)
- Association of Daily Eating Duration and Day-To-Day Variability in the Timing of Eating With Fatal Cancer Risk in Older Men (2022)
- Could a good night's sleep improve COVID-19 vaccine efficacy? (2021)
- Meal and Sleep Timing before and during the COVID-19 Pandemic (2021)
- Sleep in Female Healthcare Workers during COVID-19 (2021)
- Social Jetlag Changes During the COVID-19 Pandemic as a Predictor of Insomnia - A Multi-National Survey Study (2021)
- Sleep and circadian rhythms (2021)
- The association between high risk of sleep apnea, comorbidities, and risk of COVID-19 (2021)
- NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding (2021)
- Evening-types show highest increase of sleep and mental health problems during the COVID-19 pandemic - Multinational study on 19,267 adults. (2021)
- Insomnia, anxiety, and depression during the COVID-19 pandemic (2021)
- Gut microbiome as a therapeutic target in the treatment of sleep disorders (2021)
- Sleep and daytime problems during the COVID-19 pandemic and effects of coronavirus infection, confinement and financial suffering (2021)
- Effects of acute sleep loss on diurnal plasma dynamics of CNS health biomarkers in young men (2020)
- NAD+ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging (2020)
- Abdominal Fat and Metabolic Health Markers but Not PNPLA3 Genotype Predicts Liver Fat Accumulation in Response to Excess Intake of Energy and Saturated Fat in Healthy Individuals (2020)
- Self-reported difficulty initiating sleep and early morning awakenings are associated with nocturnal diastolic non-dipping in older white Swedish men (2020)
- The role of exercise-induced peripheral factors in sleep regulation (2020)
- An epigenetic clock for human skeletal muscle (2020)
- Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron (2019)
- Overeating saturated fat promotes fatty liver and ceramides compared to polyunsaturated fat (2019)
- A single night of sleep loss impairs objective but not subjective working memory performance in a sex-dependent manner (2019)
- Lack of association between self-reported insomnia symptoms and clamp-derived insulin sensitivity in elderly men (2019)
- Consumer sleep trackers (2019)
- Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans (2018)
- Acute Sleep Leads To Tissue-Specific Epigenetic And Transcriptional Responses In Healthy Humans (2018)
- Self-reported sleep disturbances and prostate cancer morbidity and mortality in Swedish men (2018)
- Association between long sleep duration and increased risk of obesity and type 2 diabetes (2018)
- Aiding sleep in type 2 diabetes (2018)
- Candidate mechanisms underlying the association between sleep-wake disruptions and Alzheimer's disease (2017)
- Circadian Clock Interaction with HIF1α Mediates Oxygenic Metabolism and Anaerobic Glycolysis in Skeletal Muscle. (2017)
- Women and men are differentially affected by sleep loss with respect to cognitive performance and hunger regulation (2017)
- Learning performance is linked to procedural memory consolidation across both sleep and wakefulness (2017)
- Gut microbiota and glucometabolic alterations in response to recurrent partial sleep deprivation in normal-weight young individuals (2016)
- Decoding obesity in the brainstem. (2016)
- Sleep restriction alters plasma endocannabinoids concentrations before but not after exercise in humans (2016)
- A single night of partial sleep loss impairs fasting insulin sensitivity but does not affect cephalic phase insulin release in young men (2016)
- Learning and sleep-dependent consolidation of spatial and procedural memories are unaltered in young men under a fixed short sleep schedule (2016)
- Self-reported sleep disturbance is associated with Alzheimer's disease risk in men (2015)
- Television Watching and Effects on Food Intake (2015)
- Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men (2015)
- Short Sleep Makes Declarative Memories Vulnerable to Stress in Humans (2015)
- Determinants of Shortened, Disrupted, and Mistimed Sleep and Associated Metabolic Health Consequences in Healthy Humans (2015)
- The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling. (2015)
- Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men (2014)
- Human obesity (2014)
- Sleep duration and energy intake (2014)
- Comment on Laker et al. Exercise Prevents Maternal High-Fat Diet-Induced Hypermethylation of the Pgc-1a Gene and Age-Dependent Metabolic Dysfunction in the Offspring. Diabetes 2014; 63:1605-1611 (2014)
- Increased Impulsivity in Response to Food Cues after Sleep Loss in Healthy Young Men (2014)
- Efficacy of antibody-based therapies to treat Alzheimer's disease (2014)
- Watching TV and Food Intake (2014)
- Overfeeding Polyunsaturated and Saturated Fat Causes Distinct Effects on Liver and Visceral Fat Accumulation in Humans (2014)
- Increased prefrontal and parahippocampal activation with reduced dorsolateral prefrontal and insular cortex activation to food images in obesity (2013)
- Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet (2013)
- Acute sleep deprivation increases food purchasing in men (2013)
- Calorie anticipation alters food intake after low-caloric but not high-caloric preloads (2013)
- Sweet taste perception not altered after acute sleep deprivation in healthy young men (2013)
- Acute sleep deprivation increases portion size and affects food choice in young men (2013)
- Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract (2012)
- Comprehensive analysis of localization of 78 solute carrier genes throughout the subsections of the rat gastrointestinal tract (2011)
- The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children (2010)
- Analysis of the network of feeding neuroregulators using the Allen Brain Atlas (2008)
Books
