Srinivas Akula
Researcher at Institutionen för cell- och molekylärbiologi; Mikrobiologi och immunologi
- E-mail:
- srinivas.akula@icm.uu.se
- Visiting address:
- Husargatan 3
752 37 Uppsala - Postal address:
- Box 596
751 24 Uppsala
Researcher at Institutionen för medicinsk biokemi och mikrobiologi; Infektioner och immunitet; Gunnar Pejler
- E-mail:
- srinivas.akula@imbim.uu.se
- Visiting address:
- BMC
Husargatan 3
752 37 UPPSALA - Postal address:
- Box 582
751 23 UPPSALA
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Publications
Selection of publications
- The mast cell transcriptome and the evolution of granule proteins and Fc receptors (2019)
- Extended cleavage specificity of sheep mast cell protease-2 (2019)
- Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability (2018)
- Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster (2018)
- Extended cleavage specificity of human neutrophil cathepsin G (2018)
- The Appearance and Diversification of Receptors for IgM During Vertebrate Evolution (2017)
- Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals (2017)
- Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution (2016)
- Channel catfish granzyme-like I is a highly specific serine protease with metase activity that is expressed by fish NK-like cells (2016)
- Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution (2015)
- Fc Receptors for Immunoglobulins and Their Appearance during Vertebrate Evolution (2014)
- The mouse mast cell transcriptome
Recent publications
- Cultures of Human Skin Mast Cells, an Attractive In Vitro Model for Studies of Human Mast Cell Biology (2024)
- The Extended Cleavage Specificity of Channel Catfish Granzyme-like II, A Highly Specific Elastase, Expressed by Natural Killer-like Cells (2024)
- Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (Lepisosteus oculatus) (2024)
- Identification of the Major Protein Components of Human and Cow Saliva (2023)
- Two granzyme A/K homologs in Zebra mbuna have different specificities, one classical tryptase and one with chymase activity (2023)
All publications
Articles
- Cultures of Human Skin Mast Cells, an Attractive In Vitro Model for Studies of Human Mast Cell Biology (2024)
- The Extended Cleavage Specificity of Channel Catfish Granzyme-like II, A Highly Specific Elastase, Expressed by Natural Killer-like Cells (2024)
- Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (Lepisosteus oculatus) (2024)
- Identification of the Major Protein Components of Human and Cow Saliva (2023)
- Two granzyme A/K homologs in Zebra mbuna have different specificities, one classical tryptase and one with chymase activity (2023)
- Extended cleavage specificities of human granzymes A and K, two closely related enzymes with conserved but still poorly defined functions in T and NK cell-mediated immunity (2023)
- Analysis of the mast cell expressed carboxypeptidase A3 and its structural and evolutionary relationship to other vertebrate carboxypeptidases (2022)
- Quantitative Analysis of the Transcriptome of Two Commonly Used Human Monocytic Cell Lines-THP-1 and Mono Mac 6-Reveals Their Arrest during Early Monocyte/Neutrophil Differentiation (2022)
- Chicken cathepsin G-like - A highly specific serine protease with a peculiar tryptase specificity expressed by chicken thrombocytes (2022)
- Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems (2022)
- Extended cleavage specificity of a Chinese alligator granzyme B homologue, a strict Glu-ase in contrast to the mammalian Asp-ases (2022)
- The Evolutionary History of the Chymase Locus -a Locus Encoding Several of the Major Hematopoietic Serine Proteases (2021)
- Mast Cells and Basophils in the Defense against Ectoparasites (2021)
- Duodenases are a small subfamily of ruminant intestinal serine proteases that have undergone a remarkable diversification in cleavage specificity (2021)
- Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins (2021)
- Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity (2020)
- How Relevant Are Bone Marrow-Derived Mast Cells (BMMCs) as Models for Tissue Mast Cells? (2020)
- Extended Cleavage Specificity of the Rat Vascular Chymase, a Potential Blood Pressure Regulating Enzyme Expressed by Rat Vascular Smooth Muscle Cells (2020)
- Extended Cleavage Specificities of Two Mast Cell Chymase-Related Proteases and One Granzyme B-Like Protease from the Platypus, a Monotreme (2020)
- Potent and Broad but not Unselective Cleavage of Cytokines and Chemokines by Human Neutrophil Elastase and Proteinase 3 (2020)
- Protective role of mouse mast cell tryptase Mcpt6 in melanoma. (2020)
- Mouse Strain-Dependent Difference Toward the Staphylococcus aureus Allergen Serine Protease-Like Protein D Reveals a Novel Regulator of IL-33 (2020)
- Extended cleavage specificity of sheep mast cell protease-2 (2019)
- Highly Selective Cleavage of TH2-Promoting Cytokines by the Human and the Mouse Mast Cell Tryptases, Indicating a Potent Negative Feedback Loop on TH2 Immunity (2019)
- Extended Cleavage Specificities of Rabbit and Guinea Pig Mast Cell Chymases (2019)
- Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability (2018)
- Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster (2018)
- Extended cleavage specificity of human neutrophil cathepsin G (2018)
- Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals (2017)
- Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution (2016)
- Channel catfish granzyme-like I is a highly specific serine protease with metase activity that is expressed by fish NK-like cells (2016)
- Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution (2015)
- Fc Receptors for Immunoglobulins and Their Appearance during Vertebrate Evolution (2014)
- The mouse mast cell transcriptome
Books
Chapters
