Jan Hirsch
Professor emeritus at Department of Surgical Sciences; Odontology & Maxillofacial Surgery
- Mobile phone:
- +46 70 394 83 23
- E-mail:
- jan.hirsch@uu.se
- Visiting address:
- Käkkirurgiska kliniken
Akademiska sjukhuset ingång 7879
751 85 UPPSALA - Postal address:
- Käkkirurgiska kliniken
Akademiska sjukhuset ingång 7879
751 85 Uppsala
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Short presentation
This text is not available in English, therefore the Swedish version is shown.
I have 35 years of experience from leading and developing successful units within oral and maxillofacial surgery in the public health sector and privately. The success relies on attracting and recruiting staff, nationally and internationally that combine clinical skill and excellence in R & D in order to establish the organization in the front globally, in collaboration with best available partners in medicine and in industry.
Keywords
- 3d-printing
- cytology and ai and deep learning
- oral cancer hpv and tobacco
- oral cancer screening
- reconstructive maxillofacial surgery
Publications
Recent publications
- Dental hygienists and dentists as providers of brush biopsies for oral mucosa screening (2023)
- A paradigm shift in the prevention and diagnosis of oral squamous cell carcinoma. (2023)
- Analytical Study of Stress Distributions around Screws in Flat Mandibular Bone under In-Plane Loading (2023)
- Early Detection of Oral Potentially Malignant Disorders (2022)
- Early Detection of Oral Potentially Malignant Disorders: A Review on Prospective Screening Methods with Regard to Global Challenges (2022)
All publications
Articles
- Dental hygienists and dentists as providers of brush biopsies for oral mucosa screening (2023)
- A paradigm shift in the prevention and diagnosis of oral squamous cell carcinoma. (2023)
- Analytical Study of Stress Distributions around Screws in Flat Mandibular Bone under In-Plane Loading (2023)
- Early Detection of Oral Potentially Malignant Disorders (2022)
- Early Detection of Oral Potentially Malignant Disorders: A Review on Prospective Screening Methods with Regard to Global Challenges (2022)
- Icke-invasiv kontroll av cellförändringar i munslemhinnan (2021)
- Patient-reported pain after surgical removal of leukoplakia (2021)
- Brush Samples of Oral Lesions to FTA Elute Card for High-risk Human Papilloma Virus Diagnosis (2021)
- High-risk human papillomavirus in patients with oral leukoplakia and oral squamous cell carcinoma-A multi-centre study in Sweden, Brazil and Romania. (2021)
- Denture Guided Epithelial Regeneration (2020)
- Custom-Made Horizontal and Vertical Maxillary Augmentation with Smartbone® On Demand™ (2020)
- A simple, effective, universal, and reusable osteotomy tool for jaw reconstructions with microvascular fibula transplants (2020)
- Fibula Graft Cutting Devices (2020)
- A Deep Learning based Pipeline for Efficient Oral Cancer Screening on Whole Slide Images (2019)
- Combined Testing of p16 Tumour-suppressor Protein and Human Papillomavirus in Patients With Oral Leukoplakia and Oral Squamous Cell Carcinoma (2019)
- Recurrence rates after surgical removal of oral leukoplakia (2019)
- Screening kan minska insjuknandet i munhålecancer (2017)
- Clinical, Morphological, and Molecular Evaluations of Bone Regeneration With an Additive Manufactured Osteosynthesis Plate (2016)
- Failure location predictoin by finite element analysis for an additive manufactured mandible implant (2015)
- Nested PCR for detection of HSV-1 in oral mucosa (2015)
- Comparison Between Single PCR and Nested PCR in Detection of Human Papilloma Viruses in Paraffin-embedded OSCC and Fresh Oral Mucosa (2015)
- Association of Human Papilloma Virus infection in healthy oral mucosa, oral dysplasia and oral squamous cell carcinoma (2015)
- A computer-based comparative quantitative analysis of surgical outcome of mandibular reconstructions with free fibula microvascular flaps (2015)
- Haptics-assisted Virtual Planning of Bone, Soft Tissue, and Vessels in Fibula Osteocutaneous Free Flaps (2015)
- Virus and tobacco use in premalignant and malignant oral lesions (2015)
- Surgical approach to snus-induced injury of the oral mucosa (2014)
- A retrospective study of patients with mandibular fractures treated at a Swedish University Hospital 1999-2008 (2014)
- Smokeless tobacco, viruses and oral cancer (2014)
- Shape and volume of craniofacial cavities in intentional skull deformations (2013)
- A haptics-assisted cranio-maxillofacial surgery planning system for restoring skeletal anatomy in complex trauma cases (2013)
- Telemedicine (2012)
- Viral and Molecular Aspects of Oral Cancer (2012)
- Oral cancer in Swedish snuff dippers (2012)
- Treatment of sleep apnoea using a mandibular advancement splint (2012)
- Virus, genetic alterations and tobacco use in premalignant and malignant oral lesions (2012)
- Local Tolerance of a Sublingual Nicotine Tablet (2012)
- Differential Expression of Apoptosis, Cell Cycle Regulation and Intermediate Filament Genes in Oral Squamous Cell Carcinomas Associated with Toombak Use in Sudan (2011)
- Computer-navigated contouring of craniofacial fibrous dysplasia involving the orbit (2011)
- A 5-Year Prospective Clinical Study of Submerged and Nonsubmerged Paragon System Implants in the Edentulous Mandible (2010)
- Prevalence of viral (HPV, EBV, HSV) infections in oral submucous fibrosis and oral cancer from India (2010)
- Presence of human papilloma virus, herpes simplex virus and Epstein-Barr virus DNA in oral biopsies from Sudanese patients with regard to toombak use (2010)
- Gene expression analysis by cDNA microarray in oral cancers from two Western populations (2010)
- Anatomical Variation of Mental Foramen (2010)
- A cessation program for snuff-dippers with long-term, extensive exposure to Swedish moist snuff (2010)
- Skull base and maxillofacial fractures (2009)
- Virtual bending of mandibular reconstruction plates using a computer-aided design (2009)
- Högteknologi revolutionerar kraniomaxillofacial kirurgi (2009)
- Reconstruction of the temperomandibular joint with free fibula microvascular flaps without and with surgical guides (2009)
- A selective laser sintering guide for transferring a virtual plan to real time surgery in composite mandibular reconstruction with free fibula osseous flaps (2009)
- Making new meanings of being in the world after treatment for oral cancer (2009)
- A comprehensive classification of mandibular fractures (2008)
- Malignant tumors of the maxilla (2008)
- Living in a state of suspension - a phenomenological approach to the spouse's experience of oral cancer (2008)
- Functional reconstruction of the temporomandibular joint with a free fibular microvascular flap (2008)
- The uncanny mouth - a phenomenological approach to oral cancer (2007)
- The role of whole blood in thrombin generation in contact with various titanium surfaces (2007)
- Bone formation at the maxillary sinus floor following simultaneous elevation of the mucosal lining and implant installation without graft material (2007)
- Ways of understanding the encounter with head and neck cancer patients in the hospital dental team - a phenomenographic study (2006)
- Biological factors contributing to failures of osseointegrated oralimplants. (II) (1998)
- Biological factors contributing to failures of osseointegrated oral implants. (I) (1998)
- The Swedish snus and the Sudanese toombak (1998)
- Studies of the healing of bone grafts, and the incorporation of titanium implants in grafted bone (1998)
- Failure patterns of four osseointegrated oral implant systems (1997)
- Immunohistochemical detection of p53 in non-malignant and malignant oral lesions associated with snuff dipping in the Sudan and Sweden (1996)
- Assessment of p53 and Ki-67 expression in snuff-induced lesions (1996)
- Fixture stability and nerve function after transposition and lateralization of the inferior alveolar nerve and fixture installation (1995)
- Recrudescence of herpes simplex virus type 1 in latently infected rats after trauma to oral tissues (1993)
- Reactivated herpes simplex virus infection as a possible cause of dry socket after tooth extraction (1993)
- Measures of dental beliefs and attitudes (1993)
- Hemodynamic effects of the use of oral snuff (1992)
- Inhibition of herpes simplex virus replication and protein synthesis by non-smoked tobacco, tobacco alkaloids and nitrosamines (1992)
- Non-random chromosome rearrangements in herpes simplex virus type 1 transformed diploid CHEF cells (1992)
- Association between development of lower lip cancer and tobacco habits (1991)
- Maxillary sinus augmentation using mandibular bone grafts and simultaneous installation of implants (1991)
- Tobacco habits among teenagers in the city of Göteborg, Sweden, and possible association with dental caries (1991)
- Effect of repeated oral administration of tobacco snuff on natural killer-cell activity in the rat (1991)
- Primary herpes simplex virus (type 1) infection delays healing of oral excisional and extraction wounds in the rat (1990)
- Snuff-induced carcinogenesis (1989)
- Effects of acyclovir on herpes simplex virus type 1 infection in mice treated with 12-O-tetradecanoylphorbol 13-acetate (1989)
- Snuff tumorigenesis (1989)
- [Single tooth replacement with aid of osseointegration--a modified surgical prosthetic procedure] (1989)
- Electric or manual toothbrush? (1988)
- Autogenous free tooth transplantation in man by a 2-stage operation technique (1988)
- Single-tooth rehabilitation using osseointegration (1988)
- The reversibility of the snuff-induced lesion (1986)
- Surgical endodontic retreatment (1986)
- Inhibition of herpes simplex virus replication by tobacco extracts (1984)
- Effect of long-term application of snuff on the oral mucosa (1983)
- A clinical, histomorphological and histochemical study on snuff-induced lesions of varying severity (1982)
- Snuff-induced lesions of the oral mucosa (1981)
- Periapical surgery (1979)
Chapters
Conferences
- Visualization of convolutional neural network class activations in automated oral cancer detection for interpretation of malignancy associated changes (2019)
- Detection of Malignancy-Associated Changes Due to Precancerous and Oral Cancer Lesions: A Pilot Study Using Deep Learning (2018)
- Brush Biopsy For HR-HPV Detection With FTA Card And AI For Cytology Analysis - A Viable Non-invasive Alternative (2018)
- Deep convolutional neural networks for detecting cellular changes due to malignancy (2017)
- Finite Element Investigation of the In - Vivo Failure of a Titanium Alloy HumanJaw Implant (2014)
- Custom Mandibular Implant Design with Deformable Models and Haptics (2014)
- Snap-to-fit, a Haptic 6 DOF Alignment Tool for Virtual Assembly (2013)
