Johan Wannberg
Researcher at Institutionen för läkemedelskemi; Preparativ läkemedelskemi
- Telephone:
- +46 18 471 41 24
- Fax:
- +46 18 471 44 74
- E-mail:
- Johan.Wannberg@scilifelab.uu.se
- Visiting address:
- Uppsala Biomedicinska Centrum, BMC, Husarg. 3
- Postal address:
- Box 574
751 23 UPPSALA
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Short presentation
This text is not available in English, therefore the Swedish version is shown.
Forskare vid faciliteten Medicinal Chemistry, Lead Identification, Drug Discovery and Development Platform, Science for Life Laboratory på Inst. f. Läkemedelskemi. Information om plattformen finns på https://www.scilifelab.se/platforms/ddd.
Leg. apotekare (1999) och FarmDr i Läkemedelskemi (2005). Åtta års erfarenhet från industri och mindre forskningsbolag.
Anställd på SciLifeLab DDD/ Inst. f. Läkemedelskemi från 2014. Utvecklar från 2018 DNA-kodade substansbibliotek vid plattformen.
Publications
Recent publications
- Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress (2022)
- N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands (2021)
- A Series of Analogues to the AT2R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode (2019)
- Biological characterization of new inhibitors of microsomal PGE synthase-1 in preclinical models of inflammation and vascular tone (2019)
- A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes (2018)
All publications
Articles
- Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress (2022)
- N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands (2021)
- A Series of Analogues to the AT2R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode (2019)
- Biological characterization of new inhibitors of microsomal PGE synthase-1 in preclinical models of inflammation and vascular tone (2019)
- A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes (2018)
- Rapid and straightforward transesterification of sulfonyl carbamates (2016)
- Microwave Promoted Transcarbamylation Reaction of Sulfonylcarbamates under Continuous-Flow Conditions (2016)
- Synthesis of enantiopure angiotensin II type 2 receptor [AT(2)R] antagonist EMA401 (2015)
- Nonresonant microwave heated continuous flow synthesis in medicinal chemistry (2014)
- Microwave Heated Flow Synthesis of Spiro-oxindole Dihydroquinazolinone Based IRAP Inhibitors (2014)
- One-Pot, Two-Step, Microwave-Assisted Palladium-Catalyzed Conversion of Aryl Alcohols to Aryl Fluorides via Aryl Nonaflates (2013)
- HIV-1 Protease Inhibitors with a Transition-State Mimic Comprising a Tertiary Alcohol (2010)
- Controlled microwave heating as an enabling technology (2007)
- Stereoselective Synthesis of 3-Aminoindan-1-ones and Subsequent Incorporation into HIV-1 Protease Inhibitors (2006)
- Microwave-accelerated synthesis of protease inhibitors (2006)
- A New Structural Theme in C2-Symmetric HIV-1 Protease Inhibitors: ortho-Substituted P1/P1’ Side Chains (2006)
- Hydroxylamine as an ammonia equivalent in microwave-enhanced aminocarbonylations (2006)
- Microwave-Enhanced and Metal-Catalyzed Functionalizations of the 4-Aryl-Dihydropyrimidone Template (2005)
- High-Speed Synthesis of Potent C2-Symmetric HIV-1 Protease Inhibitors by in Situ Aminocarbonylations (2005)
- Microwave-enhanced medicinal chemistry (2004)
- Direct microwave synthesis of N,N'-diacylhydrazines and Boc-protected hydrazides by in situ carbonylations under air. (2004)
- Increasing Rates and Scope of Reactions (2003)
