Lena Holm
Professor emer. i fysiologi. -Avd. för Integrativ Fysiologi vid Institutionen för medicinsk cellbiologi; Forskargrupp Lena Holm
- Telefon:
- 018-471 43 25
- Fax:
- 018-471 49 38
- E-post:
- Lena.Holm@mcb.uu.se
- Besöksadress:
- BMC
Husargatan 3
751 23 Uppsala - Postadress:
- Box 571
751 23 UPPSALA
Professor emer. vid Institutionen för medicinsk cellbiologi; Emeriti
- Besöksadress:
- BMC
Husargatan 3
751 23 Uppsala - Postadress:
- Box 571
751 23 UPPSALA
Ladda ned kontaktuppgifter för Lena Holm vid Institutionen för medicinsk cellbiologi; Emeriti
- Akademiska meriter:
- DMSc
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Publikationer
Senaste publikationer
- Co-option of PPARα in the regulation of lipogenesis and fatty acid oxidation in CLA-induced hepatic steatosis (2021)
- Distinct B cell subsets in Peyer's patches convey probiotic effects by Limosilactobacillus reuteri (2021)
- Perivascular macrophages regulate blood flow following tissue damage (2021)
- High-Fat Diet Enriched with Bilberry Modifies Colonic Mucus Dynamics and Restores Marked Alterations of Gut Microbiome in Rats (2019)
- Dietary Fiber in Bilberry Ameliorates Pre-Obesity Events in Rats by Regulating Lipid Depot, Cecal Short-Chain Fatty Acid Formation and Microbiota Composition (2019)
Alla publikationer
Artiklar
- Co-option of PPARα in the regulation of lipogenesis and fatty acid oxidation in CLA-induced hepatic steatosis (2021)
- Distinct B cell subsets in Peyer's patches convey probiotic effects by Limosilactobacillus reuteri (2021)
- Perivascular macrophages regulate blood flow following tissue damage (2021)
- High-Fat Diet Enriched with Bilberry Modifies Colonic Mucus Dynamics and Restores Marked Alterations of Gut Microbiome in Rats (2019)
- Dietary Fiber in Bilberry Ameliorates Pre-Obesity Events in Rats by Regulating Lipid Depot, Cecal Short-Chain Fatty Acid Formation and Microbiota Composition (2019)
- Perivascular macrophages regulate blood flow following tissue damage (2018)
- Sex differences and effects of oestrogen in rat gastric mucosal defence (2017)
- Lactobacillus reuteri increases mucus thickness and ameliorates dextran sulphate sodium-induced colitis in mice (2016)
- In Vivo and In Vitro Detection of Luminescent and Fluorescent Lactobacillus reuteri and Application of Red Fluorescent mCherry for Assessing Plasmid Persistence (2016)
- The Gastrointestinal Circulation (2015)
- Physiological recycling of endogenous nitrate by oral bacteria regulates gastric mucus thickness (2015)
- CX3CR1 deficiency alters response to L-reuteri treatment of DSS-induced colitis in mice (2014)
- Preventive and therapeutic effects of nitrite supplementation in experimental inflammatory bowel disease (2014)
- γδ T-cell-deficient mice show alterations in mucin expression, glycosylation and goblet cells but maintain an intact mucus layer. (2014)
- Strategical steering of the immune system (2014)
- Propionic and butyric acids, formed in the caecum of rats fed highly fermentable dietary fibre, are reflected in portal and aortic serum (2013)
- iNOS-Dependent Increase in Colonic Mucus Thickness in DSS-Colitic Rats (2013)
- Strategic recruitment of proangiogenic leukocytes to the ischemic hindlimb increases functional tissue perfusion (2013)
- Lactobacillus reuteri Maintains a Functional Mucosal Barrier during DSS Treatment Despite Mucus Layer Dysfunction (2012)
- Assessment of mucus thickness and production in situ (2012)
- Decreased leukocyte recruitment by inorganic nitrate and nitrite in microvascular inflammation and NSAID-induced intestinal injury (2012)
- Importance and regulation of the colonic mucus barrier in a mouse model of colitis (2011)
- Inhibition of Leukocyte Recruitment by Inorganic Nitrate and Nitrite (2010)
- Bacteria Penetrate the Inner Mucus Layer before Inflammation in the Dextran Sulfate Colitis Model (2010)
- Acute effects of Helicobacter pylori extracts on gastric mucosal blood flow in the mouse (2009)
- Basal and induced NO formation in the pharyngo-oral tract influences estimates of alveolar NO levels (2009)
- Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwash (2009)
- Lactobacillus reuteri prevents colitis by reducing P-selectin-associated leukocyte- and platelet-endothelial cell interactions (2009)
- A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis (2008)
- The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria (2008)
- The gastric mucus layers (2008)
- Protection from nonsteroidal anti-inflammatory drug (NSAID)-induced gastric ulcers by dietary nitrate (2007)
- Dietary nitrate increases gastric mucosal blood flow and mucosal defense (2007)
- eNOS involved in colitis-induced mucosal blood flow increase (2007)
- Impaired mucus-bicarbonate barrier in Helicobacter pylori-infected mice (2006)
- Increased levels of mucins in the cystic fibrosis mouse small intestine and modulator effects of the Muc1 mucin expression (2006)
- An in vivo model for gastric physiological and pathophysiological studies in the mouse (2005)
- Transmural gradient of leukocyte-endothelial interaction in the rat gastrointestinal tract. (2005)
- SLC26A9 is expressed in gastric surface epithelial cells, mediates Cl-/HCO3- exchange, and is inhibited by NH4+. (2005)
- Nitrite in saliva increases gastric mucosal blood flow and mucus thickness (2004)
- Nitrite in salvia increases gastric mucosal blood flow and mucus thickness (2004)
- Reproductive impairment in Japanese quail (Coturnix japonica) after in ovo exposure to o,p'-DDT. (2003)
- Inducible nitric oxide synthase is involved in acid-induced gastric hyperemia in rats and mice (2003)
- NO-flurbiprofen maintains duodenal blood flow, enhances mucus secretion contributing to lower mucosal injury (2002)
- The importance of mucus layers and bicarbonate transport in preservation of gastric juxtamucosal pH (2002)
- Intraluminal acid and gastric mucosal integrity;the importance of blood-borne bicarbonate (2001)
- Intraluminal acid and gastric mucosal integrity (2001)
- Acid transport through channels in the mucous layer of rat stomach (2000)
- Helicobacter pylori extracts reduce gastric mucosal blood flow by a nitric oxide-independent but mast cell- and platelet-activating factor receptor-dependent pathway in rats (1999)
- Extracts of Helicobacter pylori reduce gastric mucosal blood flow through a VacA- and CagA-independent pathway in rats (1998)
- Gastric mucosal smooth muscles may explain oscillations in glandular pressure (1998)
- Prostaglandin E2 and aggressive factors increase the gland luminal pressure in the rat gastric mucosa in vivo. (1998)
- Omeprazole induces high intraglandular pressure in the rat gastric mucosa. (1997)
- Effect of inhibition of pentagastrin-stimulated acid secretion on gastric mucosal gland luminal pressure. (1997)
- Villus tip microcirculation in the rat duodenum. (1995)
- Mucus and alkali secretion in the rat duodenum (1995)
- Histamine is not involved in pentagastrin-induced gastric mucosal vasodilation in the rat. (1994)
- Exposure of the duodenum to high concentrations of hydrochloric acid. Effects on mucosal permeability, alkaline secretion, and blood flow. (1994)
- Hydrogen ion concentration in the mucus layer on top of acid-stimulated and -inhibited rat gastric mucosa. (1994)
- Influence of tactile stimulation of the rat gastric mucosa on blood flow and acid output. (1993)
- Duodenal mucosal alkaline secretion, permeability, and blood flow. (1993)
- Vasoactive intestinal polypeptide reduces hydrochloric acid-induced duodenal mucosal permeability. (1993)
- Stimulation of acid secretion increases the gastric gland luminal pressure in the rat. (1992)
- Role of prostaglandins in regulation of gastric mucosal blood flow and acid secretion. (1992)
- Renal interstitial pressure and tubuloglomerular feedback control in rats during infusion of atrial natriuretic peptide (ANP). (1992)
- Effects of cigarette smoke and nicotine on duodenal bicarbonate secretion in the rabbit and the rat. (1990)
- Microscopy of acid transport at the gastric surface in vivo. (1990)
- Duodenal alkaline secretion in rabbits (1990)
- Resetting of the pressure range for blood flow autoregulation in the rat kidney. (1990)
- Effects of hypovolemia on blood flow, arterial [HCO3-], and HCO3- output in the rat duodenum. (1990)
- Effects of omeprazole on gastric mucosal microcirculation and acid secretion in the rat (1987)
- Role of neutrophils in hemorrhagic shock-induced gastric mucosal injury in the rat (1987)
- A probabilistic approach for evaluating a technique for an indirect monitoring of the capillary blood flow to the gastric parietal cells (1987)
- Effects of prostaglandin E1, E2 and 16,16-dimethyl-E2 on gastric mucosal microcirculation and basal acid output in the rat (1986)
- Pentagastrin and gastric mucosal blood flow (1986)
- Rat gastric mucosal microcirculation in vivo (1985)
- Autoregulation of gastric blood flow and oxygen uptake (1981)
- Oral bacteria regulate gastric mucosal defense via bioactivation of dietary nitrate
- Influence of Lactobacillus reuteri on the colonic microbiota in health and DSS-induced colitis
- iNOS-dependent increase in colonic mucus thickness in DSS-colitic rats
- Uncovering a new role for immune cells