I am interested in how v-SNAREs and SNARE accessory proteins regulate the secretory dynamics of cytotoxic lymphocytes and pancreatic beta cells. We study how granule maturation in the endosomal and secretory pathway can regulate fusion in the secretory pathway by examining the temporal and spatial kinetics of individual granules as they approach the membrane and undergo exocytosis. These studies will allow us to quantify the secretory machinery assembly with temporal kinetics of exocytosis.
Nyckelord: insulin secretion regulated secretion v-snares
Kontakta katalogansvarig vid den aktuella organisationen (institution eller motsv.) för att rätta ev. felaktigheter.