Siv Jönsson

I am affiliated to the Pharmacometrics group focused on non-linear mixed effects models, i.e. mathematical models i) describing how concentrations and effects of medicines change over time and vary between patients and ii) used in optimizing drug therapy and drug development.

I work together with Mats Karlsson, Elisabet Nielsen and Lena Friberg in projects related to model-based individualized treatment, immunology and oncology

Dr Siv Jönsson was a senior researcher in the Pharmacometric group within the Department of Pharmacy, Uppsala University, Sweden, headed by Professor Mats O Karlsson, up until end of 2023. Siv earned an MSc degree in 1988 and has thereafter been working in the pharmacokinetic, pharmacodynamic and pharmacometric areas in three environments: the pharmaceutical industry, the regulatory agency, in academia and in pharmacometric consultancy.

In total 5 years were spent within industry (Kabi Pharmacia, Astra Zeneca) working with clinical pharmacology and pharmacometrics. Furthermore, Siv worked as a pharmacokinetic assessor within the Swedish regulatory authority (Medical Products Agency) in 2 periods (in total 9 years, latest period 2007-2011). Finally, the academic years include her PhD education (PhD obtained in 2004), 2 years as senior lecturer and 12 years as researcher; all these years dealing with methodological and applied pharmacometric projects, where applied projects relate to e.g. renal transplant patients and haemophilia A/B patients. Since 2019, Siv is an employee of Pharmetheus AB, Uppsala, Sweden, but keeps an affiliation with the Pharmacometrics group.

Siv has published approximately 50 peer-reviewed research articles and book chapters and is currently the co-supervisor of 4 PhD students.