Victor Agmo Hernandez
Senior Lecturer/Associate Professor at Institutionen för läkemedelskemi; Farmaceutisk fysikalisk kemi
- E-mail:
- victor.agmo@ilk.uu.se
- Visiting address:
- Biomedicinskt Centrum BMC, Husargatan 3
- Postal address:
- Box 574
751 23 UPPSALA
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Short presentation
I am interested in self-associated lipid systems and surface chemistry. The use of surface sensitive techniques for the study of the properties of lipid membranes and their interactions with solutes is the main focus of my research. Among others, I apply electrochemical and nanogravimetric (QCM-D) methods to the study of lipid modified substrates and the interactions of lipid membranes with peptides, proteins and inorganic material.
Biography
I obtained the title of B.Sc. in Chemical Sciences from the Monterrey Institute of Technology, Monterrey, Mexico, in December 2002. After a brief experience at the industry (CEMEX, Mexico), in 2004 I moved to Germany to pursue Ph.D studies at the University of Greifswald, obtaining the degree of Dr. rer. nat. in Analytical Chemistry in 2008. My Ph.D. thesis focused on describing the mechanism of adhesion of giant unilamellar vesicles on mercury electrodes. In May 2008 I moved to Sweden to start a postdoc at Uppsala University, working in physical chemistry studies on the behavior of lipid membranes. Since 2013 I am a researcher at the Department of Chemistry-BMC at Uppsala University, where I was appointed as Associated Professor (Docent) in 2014. Currently, I am senior lecturer at the Department of Pharmacy, Uppsala University.
Publications
Selection of publications
- Electrochemistry of Adhesion and Spreading of Lipid Vesicles on Electrodes (2013)
- Physicochemical Characterization of Phosphopeptide/Titanium Dioxide Interactions Employing the Quartz Crystal Microbalance Technique (2013)
- Immobilized lipodisks as model membranes in high-throughput HPLC-MS analysis (2013)
- Ubiquinone-10 in gold-immobilized lipid membrane structures acts as a sensor for acetylcholine and other tetraalkylammonium cations (2012)
- Intrinsic Heterogeneity in Liposome Suspensions Caused by the Dynamic Spontaneous Formation of Hydrophobic Active Sites in Lipid Membranes (2011)
- Mesoporous TiO2-Based Experimental Layout for On-Target Enrichment and Separation of Multi- and Monophosphorylated Peptides Prior to Analysis with Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry (2011)
- Optimized Protocol for On-Target Phosphopeptide Enrichment Prior to Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry Using Mesoporous Titanium Dioxide (2010)
- The overall adhesion-spreading process of liposomes on a mercury electrode is controlled by a mixed diffusion and reaction kinetics mechanism (2009)
- Study of the temporal distribution of the adhesion-spreading events of liposomes on a mercury electrode (2009)
- The lipid composition determines the kinetics of adhesion and spreading of liposomes on mercury electrodes (2008)
- The electrochemistry of liposomes (2008)
- The adhesion and spreading of thrombocyte vesicles on electrode surfaces (2008)
- One redox probe (dmfc) can drive the transfer of anions and cations across the aqueous electrolyte ionic liquid interface (2006)
- Kinetics of the adhesion of DMPC liposomes on a mercury electrode. Effect of lamellarity, phase composition, size and curvature of liposomes, and presence of the pore forming peptide Mastoparan X (2006)
Recent publications
- A closer look at calcium-induced interactions between phosphatidylserine-(PS) doped liposomes and the structural effects caused by inclusion of gangliosides or polyethylene glycol- (PEG) modified lipids (2024)
- An overview of surface forces and the DLVO theory (2023)
- Improved accuracy and reproducibility of spontaneous liposome leakage measurements by the use of supported lipid bilayer-modified quartz cuvettes (2023)
- Dissolution mechanism of supported phospholipid bilayer in the presence of amphiphilic drug investigated by neutron reflectometry and quartz crystal microbalance with dissipation monitoring (2022)
- Avoiding artifacts in liposome leakage measurements via cuvette- and liposome-surface modifications (2022)
All publications
Articles
- A closer look at calcium-induced interactions between phosphatidylserine-(PS) doped liposomes and the structural effects caused by inclusion of gangliosides or polyethylene glycol- (PEG) modified lipids (2024)
- An overview of surface forces and the DLVO theory (2023)
- Improved accuracy and reproducibility of spontaneous liposome leakage measurements by the use of supported lipid bilayer-modified quartz cuvettes (2023)
- Dissolution mechanism of supported phospholipid bilayer in the presence of amphiphilic drug investigated by neutron reflectometry and quartz crystal microbalance with dissipation monitoring (2022)
- Avoiding artifacts in liposome leakage measurements via cuvette- and liposome-surface modifications (2022)
- Adhesion and Structural Changes of PEGylated LipidNanocarriers on Silica Surfaces (2021)
- Tumor-Targeted Delivery of the p53-Activating Peptide VIP116 with PEG-Stabilized Lipodisks (2020)
- A combination of electrochemistry and mass spectrometry to monitor the interaction of reactive species with supported lipid bilayers (2020)
- Osmoprotective effect of ubiquinone in lipid vesicles modelling the E. coli plasma membrane (2019)
- Gel Phase 1,2-Distearoyl-sn-glycero-3-phosphocholine-Based Liposomes Are Superior to Fluid Phase Liposomes at Augmenting Both Antigen Presentation on Major Histocompatibility Complex Class II and Costimulatory Molecule Display by Dendritic Cells in Vitro (2019)
- Effect of ubiquinone-10 on the stability of biomimetic membranes of relevance for the inner mitochondrial membrane. (2018)
- Choice of cuvette material can influence spectroscopic leakage and permeability experiments with liposomes. (2018)
- Radioiodination Of Small Stapled Peptides For p53 Therapy (2017)
- Lipodisks integrated with weak affinity chromatography enable fragment screening of integral membrane proteins (2016)
- Optimization of Lipodisk Properties by Modification of the Extent and Density of the PEG Corona (2016)
- Characterizing and controlling the loading and release of cationic amphiphilic peptides onto and from PEG-stabilized lipodisks (2016)
- Ubiquinone-10 alters mechanical properties and increases stability of phospholipid membranes (2015)
- Cooperative adsorption behavior of phosphopeptides on TiO2 leads to biased enrichment, detection and quantification (2015)
- Label-Free Characterization of Peptide-Lipid Interactions Using Immobilized Lipodisks (2013)
- Enhanced interpretation of adsorption data generated by liquid chromatography and by modern biosensors (2013)
- The theory of metal electronucleation applied to the study of fundamental properties of liposomes (2013)
- On-target titanium dioxide-based enrichment for characterization of phosphorylations in the Adenovirus pIIIa protein (2013)
- Physicochemical Characterization of Phosphopeptide/Titanium Dioxide Interactions Employing the Quartz Crystal Microbalance Technique (2013)
- Immobilized lipodisks as model membranes in high-throughput HPLC-MS analysis (2013)
- Ubiquinone-10 in gold-immobilized lipid membrane structures acts as a sensor for acetylcholine and other tetraalkylammonium cations (2012)
- Intrinsic Heterogeneity in Liposome Suspensions Caused by the Dynamic Spontaneous Formation of Hydrophobic Active Sites in Lipid Membranes (2011)
- Mesoporous TiO2-Based Experimental Layout for On-Target Enrichment and Separation of Multi- and Monophosphorylated Peptides Prior to Analysis with Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry (2011)
- Optimized Protocol for On-Target Phosphopeptide Enrichment Prior to Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry Using Mesoporous Titanium Dioxide (2010)
- The overall adhesion-spreading process of liposomes on a mercury electrode is controlled by a mixed diffusion and reaction kinetics mechanism (2009)
- Study of the temporal distribution of the adhesion-spreading events of liposomes on a mercury electrode (2009)
- The lipid composition determines the kinetics of adhesion and spreading of liposomes on mercury electrodes (2008)
- The electrochemistry of liposomes (2008)
- The adhesion and spreading of thrombocyte vesicles on electrode surfaces (2008)
- Reply to the comment on kinetics of the adhesion of DMPC liposomes on a mercury electrode. Effect of lamellarity, phase composition, size and curvature of liposomes, and presence of the pore forming peptide mastoparan X (2007)
- Studying ion transfers across a room temperature ionic liquid vertical bar aqueous electrolyte interface driven by redox reactions of lutetium bis(tetra-tert-butylphthalocyaninato) (2007)
- One redox probe (dmfc) can drive the transfer of anions and cations across the aqueous electrolyte ionic liquid interface (2006)
- Kinetics of the adhesion of DMPC liposomes on a mercury electrode. Effect of lamellarity, phase composition, size and curvature of liposomes, and presence of the pore forming peptide Mastoparan X (2006)
- Kinetics of liposome adhesion on a mercury electrode (2005)
Chapters
Conferences
- Radioiodination Of Small Stapled Peptides For p53 Therapy (2017)
- Intrinsic Heterogeneity in Liposome Suspensions Caused by the Dynamic Spontaneous Formation of Hydrophobic Active Sites in Lipid Membranes (2012)
- Immobilization of Lipid Bilayer Disks on QCM-D Sensors for the Study of Peptide-Lipid Interactions (2012)