Sara Roslin
Visiting researcher at Institutionen för läkemedelskemi; Preparativ läkemedelskemi
- Visiting address:
- Uppsala Biomedicinska Centrum, BMC, Husarg. 3
- Postal address:
- Box 574
751 23 UPPSALA
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Short presentation
This text is not available in English, therefore the Swedish version is shown.
To visualize memory loss, that is the goal with my research. As a Ph D student at the division of the Preclincal PET Platform, department of Medicinal Chemistry I synthesize potential PET tracers for a target located inside cholinergic neurons. Novel compounds are labeled with the short-lived nuclide carbon-11 and evaluated for their potential use as a PET tracer.
Publications
Selection of publications
- Mild and Low-Pressure fac-Ir(ppy)3-Mediated Radical Aminocarbonylation of Unactivated Alkyl Iodides through Visible-Light Photoredox Catalysis (2016)
- Synthesis and Labelling of a Piperazine-Based Library of 11C-Labeled Ligands for Imaging of the Vesicular Acetylcholine Transporter (2014)
- Novel Peptidomimetic Hepatitis C Virus NS3/4A Protease Inhibitors Spanning the P2–P1′ Region (2014)
- Synthesis and biological evaluation of a piperazine-based library of C-11-Labeled PET tracers for imaging of the vesicular acetylcholine transporter (2013)
- Novel peptidomimetic HCV NS3 protease inhibitors spanning the P2-P1´ region
Recent publications
- Acute nicotine exposure blocks aromatase in the limbic brain of healthy women (2023)
- Acyl Amidines by Pd-Catalyzed Aminocarbonylation (2023)
- First-in-human evaluation of [18F]CETO (2023)
- Palladium-Mediated Synthesis of [Carbonyl-11C]acyl Amidines from Aryl Iodides and Aryl Bromides and Their One-Pot Cyclization to 11C-Labeled Oxadiazoles (2022)
- A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media (2021)
All publications
Articles
- Acute nicotine exposure blocks aromatase in the limbic brain of healthy women (2023)
- Acyl Amidines by Pd-Catalyzed Aminocarbonylation (2023)
- First-in-human evaluation of [18F]CETO (2023)
- Palladium-Mediated Synthesis of [Carbonyl-11C]acyl Amidines from Aryl Iodides and Aryl Bromides and Their One-Pot Cyclization to 11C-Labeled Oxadiazoles (2022)
- A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media (2021)
- Synthesis of 11C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation (2017)
- Synthesis and In Vitro Evaluation of 5-Substituted Benzovesamicol Analogs containing N-Substituted Amides as Potential Positron Emission Tomography Tracers for the Vesicular Acetylcholine Transporter (2017)
- Visible-Light Photocatalysis as an Enabling Tool for the Functionalization of Unactivated C(sp(3))-Substrates (2017)
- Palladium and Visible-Light Mediated Carbonylative Suzuki-Miyaura Coupling of Unactivated Alkyl Halides and Aryl Boronic Acids (2017)
- Mild and Low-Pressure fac-Ir(ppy)3-Mediated Radical Aminocarbonylation of Unactivated Alkyl Iodides through Visible-Light Photoredox Catalysis (2016)
- Mild and Low-Pressure fac-Ir(ppy)3-Mediated Radical Aminocarbonylation of Unactivated Alkyl Iodides through Visible-Light Photoredox Catalysis (2016)
- Synthesis and Labelling of a Piperazine-Based Library of 11C-Labeled Ligands for Imaging of the Vesicular Acetylcholine Transporter (2014)
- Novel Peptidomimetic Hepatitis C Virus NS3/4A Protease Inhibitors Spanning the P2–P1′ Region (2014)
- Synthesis and biological evaluation of a piperazine-based library of C-11-Labeled PET tracers for imaging of the vesicular acetylcholine transporter (2013)
- Novel peptidomimetic HCV NS3 protease inhibitors spanning the P2-P1´ region
- Acylamidines by Pd-Catalyzed Aminocarbonylation: One-Pot Cyclizations and 11C-Labeling
Books
